Omega-3, CoQ10, magnesium and soluble fiber each have randomized-trial evidence behind them for cardiovascular health. Here is what the clinical literature actually shows on dosage, what the Q-Symbio and REDUCE-IT trials found, and how to combine the four safely.

CoQ10 is one of the most researched supplements for cardiovascular health. A 2025 meta-analysis of 45 randomized trials is the most comprehensive look at its effects on blood pressure yet. Here's what it found.